1. Product Identification

• Product Name: (R)-4-Amino-3-phenylbutanoic acid
• Synonyms: (R)-Phenibut, (3R)-4-Amino-3-phenylbutanoic acid, R-(-)-β-Phenyl-GABA
• CAS Number: 35568-36-6
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22 g/mol

2. Specifications

• Purity: ≥98.0% (HPLC)
• Enantiomeric Excess (ee): ≥99.0%
• Appearance: White to off-white crystalline powder
• Melting Point: 193–195 °C
• Loss on Drying: ≤0.5%
• Residue on Ignition: ≤0.1%
• Heavy Metals: ≤10 ppm
• Storage Condition: 2–8 °C, sealed, protect from light

3. Physical & Chemical Properties

• Density: 1.2±0.1 g/cm³
• Boiling Point: 327.8±30.0 °C (760 mmHg)
• Solubility:
  • Water: Slightly soluble
  • DMSO: ~35 mg/mL
  • Ethanol: Sparingly soluble
• LogP: -1.6
• pH (1% aqueous): ~5.5–6.5

4. Applications

• Pharmaceutical Intermediate: For synthesis of GABA analogues, neuroprotective agents
• Research Tool: Used in neuroscience, anxiety, and sleep disorder studies
• Mechanism: GABA-B receptor agonist, anxiolytic and sedative effects

5. Handling & Safety

• Avoid: Inhalation, skin/eye contact
• Wear: Gloves, goggles, lab coat
• Storage: Keep tightly closed at 2–8 °C
• Disposal: Follow local environmental regulations